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It plays essential roles in immune signalling, digestion, and even brain function

The low molecular weight peptides (~10 kDa) can cross the blood-brain barrier, theoretically delivering neurotrophic support directly to neurons

Other treatment options include behavioral therapies such as deep brain stimulation, which try to replace or manage tics by changing brain activity

GLP-1R knockdown abrogates the protective effects of liraglutide on ischaemic stroke via inhibition of M2 polarisation and activation of NLRP3 inflammasome by reducing Nrf2 activation

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